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Hexarelin Explained

by Anthony Roberts Hexarelin is a growth hormone secretagogue developed by Mediolanum Farmaceutici, and as its name might suggest, is is a hexapeptide that causes the body to release more growth hormone. It’s bioavailable through numerous methods of administration (in…

Tamoxifen works differently

The working mechanism of anti-oestrogen tamoxifen citrate – active ingredient of Nolvadex – is more complex than underground manuals would have you believe. Researchers at Duke University discovered this when they did tests on cells. And their findings are probably…

Understanding S.A.R.M.S – Part 1

by Mike Arnold Whenever the subject of S.A.R.M’s is mentioned during conversation, most people tend to think of steroids, or more specifically “steroid alternatives”. This is understandable, given that this class of drugs was originally developed for this purpose, but…

GW-501516 Explained

THE ULTIMATE PERFORMANCE ENHANCER GW-501516 is a drug that acts as a PPARδ modulator. GW-501516 is a selective agonist (activator) of the PPARδ receptor. It displays high affinity (Ki = 1 nM) and potency (EC50 = 1 nM) for PPARδ…

Combining IGF-1 and GH

It would of course be expensive, but in theory there’s a lot to be said for combining growth hormone [structure shown below] and IGF-1, writes the Dutch endocrinologist Joop Janssen in an article in Reviews in Endocrine Metabolic Disorders. The…

Growth Hormone Peptides Explored

by Mike Arnold GHRP-6: Growth hormone releasing peptide-6 (GHRP-6) is in the category of drugs known as GH Secretagogues. This category of drugs includes GHRP-2, GHRP-6, Ipamorelin, and Hexarelin. Their primary function is to stimulate the pituitary gland to produce…

Peptide Long R3 IGF-1

The use of peptides by bodybuilders is still relatively new… so in an attempt to find out more about their applications and benefits I interviewed one of the premier research scientists at a lab responsible for their production. In the…

SARM LGD-4033

by Mike Arnold For those who are unfamiliar with the term S.A.R.M, let me fill you in. S.A.R.M.’s, which is short for selective androgen receptor modulators, are a new class of drugs designed to provide the anabolic (i.e. tissue building)…

SARM MK-2866 (Ostarine)

SARM MK-2866 (Ostarine) by Mike Arnold S.A.R.M.S represent a new and exciting category of performance enhancing drugs which are unique to the PED marketplace. For those of you who are unfamiliar, we will begin with a brief introduction. The word…

What are Peptides?

Peptides are chains of amino acids joined by what chemists call amide bonds, although biologists typically call them peptide bonds instead. Large peptides are called proteins and are ubiquitous — all forms of life on Earth have proteins. The term…

Growth Hormone (hGH) Peptides Explored

by Mike Arnold GHRP-6: Growth hormone releasing peptide-6 (GHRP-6) is in the category of drugs known as GH Secretagogues. This category of drugs includes GHRP-2, GHRP-6, Ipamorelin, and Hexarelin. Their primary function is to stimulate the pituitary gland to produce…

Hexarelin Peptide Explored

by Mike Arnold Hexarelin belongs to the category of drugs known as GHRP’s (growth hormone releasing peptides), which are also sometimes referred to as GH secretagogues. They include GHRP-2, GHRP-6, Ipamorelin, and Hexarelin. Hex’s primary function is to stimulate the…

Ipamorelin Stimulates hGH

by Mike Arnold Belonging to the category of drugs known as GH secretagogues, Ipamorelin’s primary function is to stimulate the release growth hormone from the pituitary gland. Its fairly recent entrance into the marketplace has earned it the distinction of…

Peptides & Bodybuilding

by Mike Arnold It has been about a decade since peptides were introduced to the BB’ing community on a large scale. Prior to that time, there were rumblings of IGF-1 being circulated among some of the top pros, but by…

IGF-1 Explored

by Mike Arnold There is no denying that growth hormone is one of the most popular BB’ing drugs in use today and for good reason. It not only enhances the rate of fat loss, but leads to improvements in muscular…

Introduction to Pramipexole

by Mike Arnold Diagnosing the Problem In today’s ultra-competitive society, the use of performance enhancing drugs in sport has become commonplace, enabling athletes to attain a degree of athletic prowess inconceivable to previous generations. While the performance advantages associated with…

Introduction to Exemestane

by Mike Arnold Estrogen and the Bodybuilder The human body is an incredibly complex and precise organism, capable of self-regulating all aspects of its internal environment down to the most minute level of functioning. Under normal circumstances this highly interconnected…

Tadalafil Citrate (Cialis) Explored

by Mike Arnold With drug-based performance enhancement now being utilized for a multitude of purposes in nearly every sector of society, the idea that one can gain an advantage through pharmaceutical assistance is no longer looked down upon like it…

ACE-083: Myostatin Inhibitor

by Mike Arnold Will this Site Enhancing Wonder Drug Change the Bodybuilding World Forever? After years of immersing myself in the world of PED culture, I have to admit that I have found myself exhibiting decreased levels of interest over…

Letrozole Explored

by Mike Arnold With most of the focus on Aromasin these days, I wanted to bring some of the attention back to our other AI’s. While Aromasin has rightly earned its place on the most popular list, each AI has…

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