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ACE-031

$119.99 $84.99

ACE-031 1mg

43 in stock

SKU: ACE-031 Category:

Description

ACE-031 1mg

Activin receptor type-2B (ACE-031) is a protein that in humans is encoded by the ACVR2B gene. ACVR2B is an activin type 2 receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.

WARNING: This product is for research use only. It is NOT for human use and can be harmful if ingested into the body. It is for research laboratory use only and all dosage amounts for non-human use and only research use must be consulted with by a trained professional. This product is NOT in a sterile solution and is NOT to be injected. It should only be handled by licensed, qualified professionals. It is not a drug, food, or cosmetic and should not be misbranded, misused or mislabeled as a drug, food or cosmetic. It is a research chemical for research purposes.

Additional information

Weight 1 oz